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Neonatal pain score after use of paracetamol: Is there a relationship with serum trough concentration at steady state in preterm and term neonates?

Roland B van den Berg,A R Céleste Laarman,Lourens T Bloem,Jacob A Dijkstra,Agnes I Veldkamp,Karel Allegaert,Eleonora L Swart,Mirjam M van Weissenbruch

International journal of clinical pharmacology and therapeutics（2023）

Cited 0|Views6
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Abstract
No association was found between the serum trough concentration and 24-hour AUC of paracetamol at steady state and differences in pain scores in preterm and term neonates. Future research is needed to prospectively determine a patient-friendly biomarker to optimize the treatment with paracetamol.
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neonatal pain score,paracetamol,serum trough concentration
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