Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition.
Arteriosclerosis, thrombosis, and vascular biology(2023)
摘要
These data demonstrate for the first time the need for dual platelet receptor (PAR [protease-activated receptor] and FcγRIIA) stimulation for fibrin formation in HIT in vivo. These results extend our understanding of HIT pathophysiology and provide a scientific rationale for targeting the procoagulant phenotype as a possible therapeutic strategy in HIT.
更多查看译文
关键词
procoagulant phenotype,heparin-induced
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要