Systematic Analysis of the Mechanism of Polygoni Multiflori Caulis in Improving Depressive Disorder in Mice via Network Pharmacology Combined with Ultra-High Performance Liquid Chromatography Coupled with Quadrupole Exactive Orbitrap Mass Spectrometer.
Combinatorial chemistry & high throughput screening（2023）
Abstract
PMC is a relatively safe antidepressant herbal medicine with its potential mechanism involving multiple compounds, targets, and pathways.
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Key words
Depressive disorder, Polygoni Multiflori Caulis, safety evaluation, network pharmacology, ultra-high performance liquid chromatography, gene ontology
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