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The Prognostic Value of TTF-1/NKX2-1 in Lung Squamous Cell Carcinoma.

Yida Liao,Fan Yang,Xiao Li,Kezhong Chen,Jun Wang

Applied immunohistochemistry & molecular morphology : AIMM（2023）

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Abstract
TTF-1 was largely located in the nucleus of ADC, while it always accumulated in the cytoplasm of SCC. The higher level of TTF-1 in the different subcellular locations of ADC and SCC was an independent, favorable prognostic factor, respectively. Increased TTF-1 in the cytoplasm of SCC was associated with a longer OS and DFS.
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TTF-1, prognostic factor, lung cancer, squamous cell carcinoma
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