Loss of LncRNA DUXAP8 synergistically enhanced sorafenib induced ferroptosis in hepatocellular carcinoma via SLC7A11 de-palmitoylation.
Clinical and translational medicine（2023）
摘要
Our findings suggest that a novel translational strategy combining sorafenib with DUXAP8 silencing to overcome drug resistance may improve treatment efficacy in patients with advanced HCC.
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关键词
DUXAP8, ferroptosis, hepatocellular carcinoma, sorafenib resistance
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