Atherosclerosis-associated endothelial dysfunction is promoted by miR-199a-5p/SIRT1 axis regulated by circHIF1ɑ.

Shan Qiao, Xing Wang,Haiyun Li, Canling Zhang,Aihua Wang,Shanchao Zhang

Nutrition, metabolism, and cardiovascular diseases : NMCD(2023)

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摘要
Our study demonstrated the vital role of miR-199a-5p/SIRT1 axis regulated by circHIF1ɑ in AS pathogenesis and provided novel effective targets for AS treatment.
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关键词
circHIF1ɑ,miR-199a-5p,SIRT1,Endothelial cell,Atherosclerosis
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