The correlation between changes in gray matter microstructure and cerebral blood flow in Alzheimer's disease.

Xiaoxi Niu,Ying Guo, Zhongyu Chang,Tongtong Li,Yuanyuan Chen,Xianchang Zhang,Hongyan Ni

Frontiers in aging neuroscience（2023）

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摘要

Gray matter microstructure and CBF are closely related in AD. Increased MD, decreased FA, and MK are accompanied by decreased blood perfusion throughout the AD course. Furthermore, CBF values are valuable for the predictive diagnosis of MCI and AD. GM microstructural changes are promising as novel neuroimaging biomarkers of AD.

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关键词

cerebral blood flow,gray matter microstructure,alzheimers,blood flow

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