Age-dependent increase in tau phosphorylation at serine 396 in Huntington's disease pre-frontal cortex.
Tiziana Petrozziello,Sommer S Huntress,Ayleen L Castillo-Torres,James P Quinn,Theresa R Connors,Corinne A Auger,Alexandra N Mills,Spencer E Kim,Sophia Liu, Farah Mahmood,Adel Boudi,Muzhou Wu,Ellen Sapp,Pia Kivisäkk,Shekar R Sunderesh,Mahmoud A Pouladi,Steven E Arnold,Bradley T Hyman,H Diana Rosas,Marian DiFiglia,Ricardo Mouro Pinto,Kimberly Kegel-Gleason,Ghazaleh Sadri-Vakili medRxiv : the preprint server for health sciences(2023)
摘要
Together these findings demonstrate that pTau-S396 levels increase significantly with age in HD PFC.
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