Impact of central venous pressure during the first 24 h and its time-course on the lactate levels and clinical outcomes of patients who underwent coronary artery bypass grafting.

An elevated mean CVP during the first 24 h was correlated with poor outcomes in patients who underwent CABG. The potential mechanisms may be influencing the lactate levels and lactate clearance through the impact on afterload of tissue perfusion. Patients whose mean CVP during the second day dropped to less than the cut-off value had favorable prognosis.