Contact system and intrinsic pathway activation in patients with advanced pancreatic cancer: a prospective cohort study.

Floris T M Bosch,Elena Campello,Frits I Mulder,Anton Ilich,Michael W Henderson, Yuriy Prokopenko,Sabrina Gavasso,Antonio Pea,Roberto Salvia,Hanneke W Wilmink,Hans-Martin Otten,Nick van Es,Nigel S Key,Harry R Büller,Paolo Simioni

Journal of thrombosis and haemostasis : JTH（2023）

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摘要

Complexes of proteases with their natural inhibitors were elevated in patients with cancer. These data suggest that the contact system and intrinsic pathway activation are increased in patients with pancreatic cancer.

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关键词

factor XI,factor XII,pancreatic neoplasm,plasma kallikrein,venous thromboembolism

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