In-Hospital Amantadine Does Not Improve Outcomes After Severe Traumatic Brain Injury: An 11-Year Propensity-Matched Retrospective Analysis.

Justin N Passman,Nathaniel A Cleri,Jordan R Saadon,Nicki Naddaf, Kevin Gilotra, Sujith Swarna,Vaibhav Vagal,Xuwen Zheng,Jason Zhang, Jeffrey Wong,Anthony Asencio, Cassie Wang,Andrew Khalili,Wei Hou,Sima Mofakham,Charles B Mikell

World neurosurgery（2023）

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摘要

Our findings do not support the early administration of amantadine for sTBI. Larger inpatient randomized trials are necessary to further investigate amantadine treatment for sTBI.

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关键词

Amantadine,Coma,Recovery of consciousness,Severe traumatic brain injury,TBI outcomes,TBI treatment

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