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The prognostic significance of tumor budding and the expression of focal adhesion kinase and survivin in lung adenocarcinoma.

Eda Yılmaz Akçay,Merih Tepeoğlu,Alev Ok Atılgan,Sergen Yağcı,Dalokay Kılıç,B Handan Özdemir

Annals of diagnostic pathology（2023）

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Abstract
A significant correlation was found between the grade of TB and pT stage, clinical stage, lymphovascular and perineural invasion in lung adenocarcinoma. TB can be considered as a histological parameter showing poor prognosis. It is thought that high expression of FAK and survivin also affect the prognosis in these patients by increasing TB.
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Key words
Lung cancer,Adenocarcinoma,Tumor budding,Survivin,Focal adhesion kinase
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