In regard to Milo et aL

Dear Editor, Response to “letter to the Editor of Radiotherapy and Oncology regarding the paper titled Radiation dose to heart and cardiac substructures and risk of coronary artery disease in early breast cancer patients: A DBCG study based on modern radiation therapy techniques”Radiotherapy and OncologyPreviewWe thank Gurlek E et al for their interest in our work regarding risk of coronary artery disease in early breast cancer patients [1,2]. The points are highly relevant. The matching criteria were thoroughly discussed before designing the study. We did not match on co-morbidity as it is not possible to investigate the effect of the matched variable. However, in the calculation of the incidence rate ratio we adjusted for previous ischemic heart disease. Full-Text PDF