Synthetic strategies for nonporous organosilica nanoparticles from organosilanes.

Organosilica nanoparticles refer to silica nanoparticles containing carbon along with organic or functional groups and can be divided into mesoporous organosilica nanoparticles and nonporous organosilica nanoparticles. During the past few decades, considerable efforts have been devoted to the development of organosilica nanoparticles directly from organosilanes. However, most of the reports have focused on mesoporous organosilica nanoparticles, while relatively few are concerned with nonporous organosilica nanoparticles. The synthesis of nonporous organosilica nanoparticles typically involves (i) self-condensation of an organosilane as the single source, (ii) co-condensation of two or more types of organosilanes, (iii) co-condensation of tetraalkoxysilane and an organosilane, and (iv) spontaneous emulsification and the subsequent radical polymerization of 3-(trimethoxysilyl)propyl methacrylate (TPM). This article aims to provide a review on the synthetic strategies of this important type of colloidal particle, followed by a brief discussion on their applications and future perspectives.