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WSD-0922, a novel brain-penetrant inhibitor of epidermal growth factor receptor, promotes survival in glioblastoma mouse models.

Jason E Conage-Pough,Sylwia A Stopka,Ju-Hee Oh,Ann C Mladek,Danielle M Burgenske,Michael S Regan,Gerard Baquer,Paul A Decker,Brett L Carlson,Katrina K Bakken,Jinqiang Zhang,Lily Liu,Claire Sun,Zhihua Mu, Wei Zhong,Nhan L Tran,William F Elmquist,Nathalie Y R Agar,Jann N Sarkaria,Forest M White

Neuro-oncology advances（2023）

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摘要
WSD-0922 is a highly potent inhibitor of EGFR in GBM, and warrants further evaluation in clinical studies.
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关键词
blood-brain barrier, EGFR, erlotinib, glioblastoma, WSD-0922
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