The local skin cellular immune response determines the clinical outcome of sarcoptic mange in Iberian ibex ( Capra pyrenaica ).

Marta Valldeperes,José Enrique Granados,Valentín Pérez,Jorge Ramón López-Olvera,Arián Ráez-Bravo,Paulino Fandos,Jesús M Pérez,Gregorio Mentaberre,Stefania Tampach,Ramón C Soriguer,José Espinosa

Frontiers in veterinary science（2023）

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Abstract

The results suggest an exacerbated but effective Th1-type cellular immune response controlling mange in Iberian ibex. Furthermore, the local immune response appears to determine the variability of the clinical responses to infestation in this species. This first report on the progression of local skin immune cells is relevant not only for individuals but also for population management and conservation.

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Key words

Capra pyrenaica, clinical outcome, experimental infestation, Iberian ibex, immunohistochemistry, inflammatory cell, sarcoptic mange (Sarcoptes scabiei), skin immune response

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