Evaluation safety and efficacy of immune checkpoint blockers (ICB) and radiotherapy combination versus ICB in non-small cell lung cancer patients with recurrence or metastasis: A systematic review and meta-analysis.

Yichun Zeng,Liying Zhang,Yichen Liang,Xian Zhang,Lei Li,Maoqi Wang,Jingliang Guo,Qiuxian Li,Jin Cao,Juan J Gu,Buhai Wang

Cancer medicine（2023）

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摘要

RT can significantly improve ORR, DCR, OS, and PFS of ICB in patients with recurrent or metastatic NSCLC without increasing toxicity. PD-1 inhibitor following SRS/SBRT could be the best option to maximally benefit the patients.

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关键词

combination therapy, immune checkpoint blockers, meta-analysis, non-small cell lung cancer, radiotherapy

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