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HMGB1/STAT3/p65 Axis Drives Microglial Activation and Autophagy Exert a Crucial Role in Chronic Stress-Induced Major Depressive Disorder.

Ke Xu,Mingyang Wang,Haiyang Wang,Shuang Zhao,Dianji Tu,Xue Gong,Wenxia Li,Xiaolei Liu,Lianmei Zhong,Jianjun Chen,Peng Xie

Journal of advanced research（2023）

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Abstract
Our study established the role of microglial HMGB1/STAT3/p65 axis in mPFC in mediating microglial activation and autophagy in MDD.
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