B-cell receptor pathway mutations are infrequent in patients with chronic lymphocytic leukemia on continuous ibrutinib therapy.

Jennifer A Woyach,Paolo Ghia,John C Byrd,Inhye E Ahn,Carol Moreno,Susan M O'Brien,Daniel Jones,Leo W K Cheung,Elizabeth Chong,Kevin Kwei,James P Dean,Danelle F James,Adrian Wiestner

Clinical cancer research : an official journal of the American Association for Cancer Research（2023）

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摘要

This systematic investigation describes development of mutations over time in patients without PD and informs the potential clinical opportunity to optimize ongoing benefits for such patients.

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