Refining Risk Stratification Among Children With Latent Rheumatic Heart Disease.

HomeCirculationVol. 147, No. 24Refining Risk Stratification Among Children With Latent Rheumatic Heart Disease No AccessLetterRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissionsDownload Articles + Supplements ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toSupplemental MaterialNo AccessLetterRequest AccessFull TextRefining Risk Stratification Among Children With Latent Rheumatic Heart Disease Andrea Beaton, Emmy Okello, Joselyn Rwebembera, Anneke Grobler, Daniel Engelman, Juliet Alepere, Jonathan Carapetis, Alyssa DeWyer, Peter Lwabi, Mariana Mirabel, Ana Olga Mocumbi, Miriam Nakitto, Emma Ndagire, Maria Carmo P. Nunes, Isaac Otim Omara, Rachel Sarnacki, Amy Scheel, Nigel Wilson, Liesl Zühlke, Ganesan Karthikeyan, Craig A. Sable and Andrew C. Steer Andrea BeatonAndrea Beaton Correspondence to: Andrea Beaton, MD, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229. Email E-mail Address: [email protected] https://orcid.org/0000-0002-4963-355X Cincinnati Children’s Hospital Medical Center, OH (A.B.). Department of Pediatrics, The University of Cincinnati School of Medicine, OH (A.B.). *A. Beaton and E. Okello contributed equally. Search for more papers by this author , Emmy OkelloEmmy Okello https://orcid.org/0000-0002-6109-0092 The Uganda Heart Institute, Kampala (E.O., J.R., J.A., P.L., M.N., E.N., I.O.O.). Department of Medicine, Makerere University, Kampala, Uganda (E.O.). *A. Beaton and E. Okello contributed equally. Search for more papers by this author , Joselyn RwebemberaJoselyn Rwebembera https://orcid.org/0000-0001-8453-818X The Uganda Heart Institute, Kampala (E.O., J.R., J.A., P.L., M.N., E.N., I.O.O.). Search for more papers by this author , Anneke GroblerAnneke Grobler Murdoch Children’s Research Institute, Melbourne, Australia (A.G., D.E., C.A.S.). Search for more papers by this author , Daniel EngelmanDaniel Engelman https://orcid.org/0000-0002-4909-1287 Murdoch Children’s Research Institute, Melbourne, Australia (A.G., D.E., C.A.S.). Melbourne Children’s Global Health, Royal Children’s Hospital, Australia (D.E., A.C.S.). Search for more papers by this author , Juliet AlepereJuliet Alepere The Uganda Heart Institute, Kampala (E.O., J.R., J.A., P.L., M.N., E.N., I.O.O.). Search for more papers by this author , Jonathan CarapetisJonathan Carapetis Telethon Kids Institute, University of Western Australia and Perth Children’s Hospital (J.C., A.C.S.). Search for more papers by this author , Alyssa DeWyerAlyssa DeWyer https://orcid.org/0000-0003-3588-2712 Virginia Tech Carilion School of Medicine, Roanoke (A.D.). Search for more papers by this author , Peter LwabiPeter Lwabi https://orcid.org/0000-0002-2895-3626 The Uganda Heart Institute, Kampala (E.O., J.R., J.A., P.L., M.N., E.N., I.O.O.). Search for more papers by this author , Mariana MirabelMariana Mirabel Assistance Publique Hôpitaux de Paris Centre, Université de Paris, Cardio-Oncologie, Hôpital Européen Georges Pompidou, France (M.M.). Search for more papers by this author , Ana Olga MocumbiAna Olga Mocumbi https://orcid.org/0000-0002-9564-2860 Instituto Nacional de Saude, Maputo, Mozambique (A.O.M.). Search for more papers by this author , Miriam NakittoMiriam Nakitto The Uganda Heart Institute, Kampala (E.O., J.R., J.A., P.L., M.N., E.N., I.O.O.). Search for more papers by this author , Emma NdagireEmma Ndagire The Uganda Heart Institute, Kampala (E.O., J.R., J.A., P.L., M.N., E.N., I.O.O.). Search for more papers by this author , Maria Carmo P. NunesMaria Carmo P. Nunes https://orcid.org/0000-0001-8801-1828 Universidade Federal de Minas Gerais, Belo Horizonte, Brazil (M.C.P.N.). Search for more papers by this author , Isaac Otim OmaraIsaac Otim Omara The Uganda Heart Institute, Kampala (E.O., J.R., J.A., P.L., M.N., E.N., I.O.O.). Search for more papers by this author , Rachel SarnackiRachel Sarnacki Children’s National Hospital, Washington, DC (R.S.). Search for more papers by this author , Amy ScheelAmy Scheel Children’s Hospital of Philadelphia, PA (A.S.). Search for more papers by this author , Nigel WilsonNigel Wilson https://orcid.org/0000-0002-0551-4655 Green Lane Paediatric and Congenital Cardiac Services, Starship Children’s Hospital, Auckland, New Zealand (N.W.). Search for more papers by this author , Liesl ZühlkeLiesl Zühlke Division of Paediatric Cardiology, Department of Paediatrics, Red Cross Children’s Hospital, Cape Town, South Africa (L.Z.). Division of Cardiology, Department of Medicine, Groote Schuur Hospital, Cape Town, South Africa (L.Z.). Search for more papers by this author , Ganesan KarthikeyanGanesan Karthikeyan https://orcid.org/0000-0002-2073-2917 All India Institute of Medical Sciences, New Delhi (G.K.). Search for more papers by this author , Craig A. SableCraig A. Sable Murdoch Children’s Research Institute, Melbourne, Australia (A.G., D.E., C.A.S.). Search for more papers by this author and Andrew C. SteerAndrew C. Steer Melbourne Children’s Global Health, Royal Children’s Hospital, Australia (D.E., A.C.S.). Telethon Kids Institute, University of Western Australia and Perth Children’s Hospital (J.C., A.C.S.). Search for more papers by this author Originally published12 Jun 2023https://doi.org/10.1161/CIRCULATIONAHA.122.063194Circulation. 2023;147:1848–1850Footnotes*A. Beaton and E. Okello contributed equally.The podcast and transcript are available with this article at https://www.ahajournals.org/doi/suppl/10.1161/CIRCULATIONAHA.122.063194.Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT03346525.For Sources of Funding and Disclosures, see page 1850.Circulation is available at www.ahajournals.org/journal/circCorrespondence to: Andrea Beaton, MD, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229. Email andrea.beaton@cchmc.orgReferences1. Beaton A, Okello E, Engelman D, Grobler A, Scheel A, DeWyer A, Sarnacki R, Omara IO, Rwebembera J, Sable C, et al. Determining the impact of benzathine penicillin G prophylaxis in children with latent rheumatic heart disease (GOAL trial): study protocol for a randomized controlled trial.Am Heart J. 2019; 215:95–105. doi: 10.1016/j.ahj.2019.06.001CrossrefMedlineGoogle Scholar2. Beaton A, Okello E, Rwebembera J, Grobler A, Engelman D, Alepere J, Canales L, Carapetis J, DeWyer A, Lwabi P, et al. Secondary antibiotic prophylaxis for latent rheumatic heart disease.N Engl J Med. 2022; 386:230–240. doi: 10.1056/NEJMoa2102074CrossrefMedlineGoogle Scholar3. US National Library of Medicine. Determining the Impact of Penicillin in Latent RHD: The GOAL Trial (GOAL).ClinicalTrials.gov identifier: NCT03346525. Accessed March 30, 2023. https://clinicaltrials.gov/ct2/show/NCT03346525Google Scholar4. Remenyi B, Wilson N, Steer A, Ferreira B, Kado J, Kumar K, Lawrenson J, Maguire G, Marijon E, Mirabel M, et al. World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease: an evidence-based guideline.Nat Rev Cardiol. 2012; 9:297–309. doi: 10.1038/nrcardio.2012.7CrossrefMedlineGoogle Scholar5. Psaki SR, Seidman JC, Miller M, Gottlieb M, Bhutta ZA, Ahmed T, Ahmed AS, Bessong P, John SM, Kang G, et al; Investigators M-EN. Measuring socioeconomic status in multicountry studies: results from the eight-country MAL-ED study.Popul Health Metr. 2014; 12:8. doi: 10.1186/1478-7954-12-8CrossrefMedlineGoogle Scholar eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. 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