Intraosseous injection of mesenchymal stem cells for the treatment of osteonecrosis of the immature femoral head and prevention of head deformity: A study in a pig model.

Sergio Martínez-Álvarez,María Galán-Olleros,Daniel Azorín-Cuadrillero,Ángel Palazón-Quevedo,África González-Murillo,Gustavo J Melen-Frajlich,Manuel Ramírez-Orellana,Tomás Epeldegui-Torre,Francisco Forriol

Science progress（2023）

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摘要

Intraosseous mesenchymal stem cells inoculation improved bone healing and remodeling in our immature pig osteonecrosis of the femoral head model. This work supports further investigation to determine whether mesenchymal stem cells enhance the healing process in immature osteonecrosis of the femoral head.

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关键词

Femoral head, osteonecrosis, pig model, hip, development, mesenchymal stem cells, Legg-Calve-Perthes disease

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