Anti-GAD65 autoantibody levels measured by ELISA and alternative types of immunoassays in relation to neuropsychiatric diseases versus diabetes mellitus type 1.

Shenghua Zong,Anita M Vinke, Peng Du,Carolin Hoffmann,Marina Mané-Damas,Peter C Molenaar,Jan G M C Damoiseaux,Mario Losen,Rob P W Rouhl,Pilar Martinez-Martinez

Frontiers in neurology（2023）

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摘要

GAD65-Abs levels are significantly higher in patients with neuropsychiatric disease than in patients with DM1/LADA, however, positivity in CBA and IHC only correlates with high levels of GAD65-Abs, and not with the underlying diseases.

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关键词

GAD65 autoantibodies, autoimmune encephalitis, epilepsy, diabetes type 1, neuronal autoantibodies, ELISA, immunohistochemistry, cell-based assay

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