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SIRT1 mediated gastric cancer progression under glucose deprivation through the FoxO1-Rab7-autophagy axis.

Mengke Zhu,Chao Wei,Haijiang Wang,Shangning Han, Lindi Cai, Xiaowen Li,Xinhua Liao,Xiangming Che,Xuqi Li,Lin Fan,Guanglin Qiu

Frontiers in oncology（2023）

Cited 2|Views16
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Abstract
The SIRT1-FoxO1-Rab7 pathway is crucial for the autophagy and malignant biological behaviors of GC cells under GD conditions, which could be a new target for the treatment of GC.
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Key words
gastric cancer, SIRT1-FoxO1-Rab7, autophagy, target treatment, glucose deprivation
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