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High JAK2V617F Variant Allele Frequency is Associated with Coronary Artery but Not Aortic Valve Calcifications in Patients with Philadelphia‐negative Myeloproliferative Neoplasms

European Journal of Haematology(2023)

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Abstract
Patients with Philadelphia‐negative myeloproliferative neoplasms (MPNs) have a higher burden of cardiac calcifications compared to the general population. It is not known whether the JAK2V617F mutation is associated with increased cardiac calcification.
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Key words
aortic valve disease,atherosclerosis,coronary,essential,Janus kinase 2,multidetector computed tomography,myelofibrosis,myeloproliferative disorders,polycythemia vera,thrombocythemia
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