Socs3 expression in myeloid cells modulates the pathogenesis of dextran sulfate sodium (DSS)-induced colitis.

Lianna Zhou,Zhaoqi Yan,Wei Yang,Jessica A Buckley,Sameer Al Diffalha,Etty N Benveniste,Hongwei Qin

Frontiers in immunology（2023）

Cited 0|Views12

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Abstract

Thus, our results suggest that deficiency of in myeloid cells exacerbates DSS-induced colitis and that prevents overt activation of the immune system in IBD. This study may provide novel therapeutic strategies to IBD patients with hyperactivated neutrophils.

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Key words

colitis,dextran sulfate sodium,myeloid cells,pathogenesis

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