Mechanical forces suppress antiviral innate immune responses from asthmatic airway epithelial cells following rhinovirus infection.

Punnam Chander Veerati,Andrew T Reid,Kristy S Nichol,Peter A B Wark,Darryl A Knight,Nathan W Bartlett,Christopher L Grainge

American journal of physiology. Lung cellular and molecular physiology（2023）

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摘要

Compressive stress mimicking bronchoconstriction inhibits anti-viral innate immune responses from asthmatic airway epithelial cells when applied prior to RV infection.

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关键词

antiviral innate immune responses, asthma, bronchoconstriction, mechanical forces, rhinovirus

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