Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword.
Journal of infection in developing countries(2023)
Abstract
Cryptococcal meningitis is an opportunistic infection associated with altered immunity. Immunomodulatory agent use in severe coronavirus disease 2019 (COVID-19) may predispose such infections. Here, we present a 75-year-old male patient who presented with fever and altered general status after severe COVID-19 infection and developed cryptococcal meningitis. Opportunistic infection may arise from the use of immunomodulation in severe COVID-19, especially in the elderly population. This article describes the case and extensively reviews cryptococcal disease post-COVID-19 literature, highlighting the risk from immunosuppressive treatment.
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Key words
cryptococcal meningitis,infection,immunomodulation,post-covid,double-edged
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