Determinants for thyroid hormone replacement therapy in subclinical hypothyroidism: a multicenter electronic health records-based study.

Among patients with subclinical hypothyroidism, female sex, and index thyrotropin level were associated with higher odds of treatment. Moreover, in our population, the decision to treat or not to treat subclinical hypothyroidism was often based on only one set of abnormal thyroid function tests, and thyroid autoimmunity assessment was underused.