Maintaining chromosome and genome stability by the RPA-RNF20-SNF2H cascade.

Generation of mouse models for COVID-19 pathogenesis is of keen interest as they would allow for efficient investigation of disease mechanisms, as well as providing a vaccine and drug development platform. However, the current transgenic hACE2 ...The classical manifestation of COVID-19 is pulmonary infection. After host cell entry via human angiotensin–converting enzyme II (hACE2), the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can infect pulmonary epithelial cells, ...