A proposal to analyze the progression of non-dialytic chronic kidney disease by surrogate endpoints: introducing parametric survival models.

Renato Erohildes Ferreira,Helady Sanders-Pinheiro,Fernando Antonio Basile Colugnati

Frontiers in medicine（2023）

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摘要

Surrogate endpoints have different hazard distributions over time, which is already recognized by nephrologists. More flexible analysis techniques that capture these relevant clinical characteristics in decision-making should be encouraged and disseminated in nephrology research.

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关键词

survival analysis,chronic kidney disease,parametric regression models,surrogate endpoint,kidney disease progression

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