Neural underpinnings of freezing-related dynamic balance control in people with Parkinson's disease.

Parkinsonism & related disorders(2023)

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摘要
Overall, we showed that decreased activation in the left MLR, and cerebellar regions in freezers relative to non-freezers could explain why dynamic balance is more affected in freezers. As non-freezers displayed increased cerebellar vermis activation compared to controls, it is possible that freezers show an inability to recruit sufficient compensatory cerebellar activity for effective dynamic balance control.
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关键词
Parkinson's disease,Freezing of gait,Balance,fMRI,Cerebellum
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