NPM3 as a novel oncogenic factor and poor prognostic marker contributes to cell proliferation and migration in lung adenocarcinoma.

Shan Wei,Jing Xing,Kaining Lu,Kai Wang,Wanjun Yu

Hereditas（2023）

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摘要

Elevated NPM3 expression predicts poor clinical outcome and an immunosuppressive microenvironment in LUAD tissues. NPM3 promotes LUAD progression by promoting cell proliferation and migration, and targeting NPM3 may represent a novel therapeutic strategy for LUAD.

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关键词

Lung adenocarcinoma, NPM3, Prognosis, Immune microenvironment, Cell proliferation, Cell migration

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