Mechanisms of Acquired Resistance to Anti-VEGF Therapy for Neovascular Eye Diseases.
Investigative ophthalmology & visual science（2023）
Abstract
Future studies of the mechanisms proposed in this review may shed some light on how these adaptations result in the development of acquired resistance to anti-VEGF therapy, which should help discover new therapeutic strategies for overcoming anti-VEGF resistance and improving clinical efficacy.
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Key words
angiogenesis, anti-vascular endothelial growth factor (VEGF), age-related macular degeneration (AMD), proliferative diabetic retinopathy (PDR), diabetic macular edema (DME)
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