Variations in mechanical stiffness alter microvascular sprouting and stability in a PEG hydrogel model of idiopathic pulmonary fibrosis.

Julie Leonard-Duke,Anthony C Bruce,Shayn M Peirce,Lakeshia J Taite

Microcirculation (New York, N.Y. : 1994)（2023）

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摘要

We have developed a novel, tunable hydrogel assay for the creation of lung explant vessel organoids which can be modulated to study the impact of specific environmental cues on vessel formation and maturation.

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关键词

angiogenesis, endothelial cells, fibrosis, hydrogel, microvascular remodeling

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