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Selective Inhibition of L-type Amino Acid Transporter 1 Suppresses Cell Proliferation in Ovarian Clear Cell Carcinoma.

Masaki Sekine,Iemasa Koh, Kosuke Nakamoto,Suguru Nosaka,Katsuyuki Tomono,Jun Sugimoto,Yoshiki Kudo

Anticancer research（2023）

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Abstract
LAT1 selective inhibition suppresses cell proliferation via the mTOR pathway by inhibiting leucine uptake in OCCC. This study illustrates the potential of using LAT1 selective inhibition as a treatment strategy for OCCC.
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Key words
suppresses cell proliferation,amino acid,cell proliferation,carcinoma,l-type
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