11- epi -Sinulariolide Acetate-induced Apoptosis in Oral Cancer Cells Is Regulated by FOXO Through Inhibition of PI3K/AKT Pathway.

Anticancer research(2023)

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摘要
A low concentration of 11-epi-SA can effectively induce apoptosis in oral cancer cells through the PI3K/AKT/FOXO pathway. 11-epi-SA has great potential as a new drug for the treatment of oral cancer.
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关键词
11-epi-sinulariolide acetate, oral squamous cell carcinoma, Sinularia flexibilis, PI3K, AKT, FOXO, apoptosis
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