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Differential expression of genes controlling lymphocyte differentiation and migration in two distinct endotypes of type 1 diabetes.

Forough Torabi,Jayakumar Vadakekolathu,Rebecca Wyatt,Pia Leete,Melissa A Tombs,Carolyn C Richardson,David J Boocock,Mark D Turner,Noel G Morgan,Sarah J Richardson,Michael R Christie

Diabetic medicine : a journal of the British Diabetic Association（2023）

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Abstract
The results provide evidence that histologically-defined type 1 diabetes endotypes differ in their immunopathology and identify inflammatory pathways specifically involved in disease developing at a young age, essential for a better understanding of disease heterogeneity.
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Key words
chemokines, chemotaxis, immunophenotyping, inflammation, lymphocytes
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