Delta (B.1.617.2) inactivated vaccine candidate elicited neutralizing antibodies to SARS-CoV-2 and circulating variants in rhesus macaques.

Yanjun Zhang,Haiyan Mao, Ju Li,Jianhua Li, Chen Huang,Jiaxuan Li, Minglei Chu, Fengbo Xue,Linhui Wang,Zhongbiao Fang,Zhen Wang, Jinan Wu,Keda Chen

Virologica Sinica（2023）

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Abstract

•The Delta inactivated vaccine constructed in this study has high immunogenicity and good safety.•The inactivated vaccine has good cross-protection against SARS-CoV-2 variants.•The vaccine exhibited high productivity and good genetic stability in production.

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Key words

rhesus macaques,vaccine candidate,neutralizing antibodies,sars-cov

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