Prenatal exposure to persistent organic pollutants and molar-incisor hypomineralization among 12-year-old children in the French mother-child cohort PELAGIE.

Emile Boyer,Christine Monfort,Fabrice Lainé,Éric Gaudreau,Hélène Tillaut,Martine Bonnaure-Mallet,Sylvaine Cordier,Vincent Meuric,Cécile Chevrier

Environmental research（2023）

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摘要

Two OCs were associated with a reduced risk of dental defects, whereas the associations between PCBs and PFASs and EDs or MIH were generally close to null or sex-specific, with an increased risk of dental defects in boys. These results suggest that POPs could impact amelogenesis. Replication of this study is required and the possible underlying mechanisms need to be explored.

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关键词

Environmental pollution, adverse effects, Dental enamel hypoplasia, Molar incisor hypomineralization, Persistent organic pollutants, Polychlorinated biphenyls, Organochlorine compound, Per-and polyfluoroalkyl substances

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