Association of circulating histone H3 and high mobility group box 1 levels with postoperative prognostic indicators in intensive care unit patients: a single-center observational study.

Ken Sawada,Yasuyo Shimomura,Daisuke Hasegawa,Tatsuhiko Harada,Tomoyuki Nakamura,Naohide Kuriyama,Yoshitaka Hara,Hidefumi Komura,Osamu Nishida

Fujita medical journal（2023）

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摘要

Histone H3 levels are correlated with severity scores and the length of ICU stay. Serum histone H3 and HMGB1 levels are elevated postoperatively. These DAMPs, however, are not prognostic indicators in postoperative ICU patients.

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关键词

histone h3,postoperative prognostic indicators,intensive care unit patients,intensive care,intensive care unit,single-center

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