Retrospective immunohistochemical analysis of human cytomegalovirus infection in the placenta and its association with fetal growth restriction.

Yusuke Funato,Yuki Higashimoto,Yoshiki Kawamura,Yoshiko Sakabe, Minori Iwakura,Masaru Ihira,Kazuya Shiogama,Masafumi Miyata,Haruki Nishizawa,Takao Sekiya,Takuma Fujii,Isao Kosugi,Tetsushi Yoshikawa

Fujita medical journal（2023）

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摘要

HCMV antigen was detected in 6.8% of placental samples obtained from FGR cases without an obvious etiology. No remarkable maternal or neonatal clinical features discriminated HCMV-related FGR from FGR due to other causes. Vasculitis and inflammation might play important roles in the pathogenesis of HCMV-related FGR.

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human cytomegalovirus,human cytomegalovirus infection,cytomegalovirus infection,placenta

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