Associations among discrimination, psychological functioning, and substance use among US Black adults aged 18–28: Moderation by racial attribution and sex

•Racial discrimination is associated with cannabis, tobacco and alcohol use in males.•Racial discrimination is associated with cannabis use in females.•Psychological distress mediated the discrimination-substance use relationship.•Nonracial and infrequent discrimination are associated with tobacco and alcohol use.•Positive wellbeing did not mediate any discrimination-substance use relationship.