Effects of Ripasudil, a Rho-Kinase Inhibitor, on Scar Formation in a Mouse Model of Filtration Surgery.

Ji-Ae Ko,Kaori Komatsu, Akira Minamoto, Satomi Kondo,Hideaki Okumichi,Kazuyuki Hirooka,Yoshiaki Kiuchi

Current eye research（2023）

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摘要

These results suggest that ripasudil, ROCK inhibitor may inhibit excessive fibrosis after glaucoma filtering surgery vis inhibition the transdifferentiation of tenon fibroblast into myofibroblast and may have a potential effect as anti-scarring for glaucoma filtration surgery.

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scar formation,filtration surgery,ripasudil,rho-kinase

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