Development of high affinity broadly reactive aptamers for spike protein of multiple SARS-CoV-2 variants.
RSC advances(2023)
摘要
We have developed broadly reactive aptamers against multiple variants by alternating the target between spike proteins from different SARS-CoV-2 variants during the selection process. In this process we have developed aptamers which can recognise all variants, from the original wild-type 'Wuhan' strain to Omicron, with high affinity ( values in the pM range).
更多查看译文
关键词
reactive aptamers,spike protein,sars-cov
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要