ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2)/Planar Cell Polarity a New Pathway Controlling Endothelial Cell Polarity Under Flow Conditions.

Pauline Bougaran,Marie-Lise Bats,Valentin Delobel,Sébastien Rubin,Juliette Vaurs,Thierry Couffinhal,Cécile Duplàa,Pascale Dufourcq

Arteriosclerosis, thrombosis, and vascular biology（2023）

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摘要

This study identified ROR2/planar cell polarity pathway as a new mechanism controlling and coordinating collective polarity patterns of EC during shear stress response.

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