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Identification of multiple novel susceptibility genes associated with autoimmune thyroid disease.

Xueying Liu,Yahu Miao,Chao Liu, Wan Lu,Qing Feng,Qiu Zhang

Frontiers in immunology（2023）

Cited 2|Views6
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Abstract
The current work provides further insight into widespread changes in AITD at the transcriptomic level, as well as characterized the genetic component of gene expression in AITD by validating identified genes, establishing new correlations, and uncovering novel susceptibility genes. Our findings indicate that the genetic component of gene expression plays a significant part in AITD.
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Key words
autoimmune thyroid disease, GWAS, TWAS, FUMA, SMR
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