Pre-exposure Prophylaxis with Tixagevimab-cilgavimab did not Reduce Severity of COVID-19 in Lung Transplant Recipients with Breakthrough Infection.

Devika Sindu,Deepika Razia,Katherine Grief,Lauren Cherrier,Ashraf Omar,Rajat Walia,Sofya Tokman

Transplantation direct（2023）

Cited 1|Views8

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Abstract

Breakthrough COVID-19 was common among LTRs despite tix-cil PrEP, possibly due to reduced efficacy of monoclonal antibodies against the Omicron variant. Tix-cil PrEP may reduce the incidence of COVID-19 in LTRs, but it did not reduce disease severity during the Omicron wave.

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Key words

lung transplant recipients,prophylaxis,pre-exposure,tixagevimab-cilgavimab

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