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Promotion effect of FGF23 on osteopenia in congenital scoliosis through FGFr3/TNAP/OPN pathway.

Hongqi Zhang,Gang Xiang,Jiong Li,Sihan He,Yunjia Wang,Ang Deng,Yuxiang Wang,Chaofeng Guo

Chinese medical journal（2023）

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Abstract
Our results suggested increased peripheral blood FGF23 levels, decreased bone mineral density in CS patients, and a good predictive ability of CS by peripheral blood FGF23 levels. FGF23 may contribute to osteopenia in CS patients through FGFr3/TNAP/OPN pathway.
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Key words
Scoliosis, Fibroblast growth factor 23, Fibroblast growth factor receptor 3, Osteopenia
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