An In-Vivo Study of the Combined Therapeutic Effects of Pulsed Non-thermal Focused Ultrasound and Radiation for Prostate Cancer.

These results suggest that RT combined with non-thermal pFUS can significantly delay the tumor growth. The mechanism of tumor cell killing between pFUS and RT may be different. Pulsed FUS shows early tumor growth delay, while RT contributes to the late effect on tumor growth delay. The addition of pFUS to RT significantly enhanced the therapeutic effect for prostate cancer treatment.