Striatal spatial heterogeneity, clustering, and white matter association of GFAP + astrocytes in a mouse model of Huntington's disease.

Frontiers in cellular neuroscience(2023)

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摘要
In summary, we showed that GFAP and S100B astrocyte subtypes are distinctly affected in HD and exist in distinct spatial arrangements that may offer new insights to the function of these specific astrocytes subtypes and their potential implications in HD pathology.
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关键词
Huntington's disease (HD), astrocytes, striatum, white matter (WM), glial fibrillary acidic protein (GFAP), S100B
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